Coatue, an American technology-focused investment manager, and Dragoneer, an American investment firm based in San Francisco, led a $140m Series B round in UpStream Healthcare, a value-based primary care services and technology company, with participation from Avidity Partners, Define Ventures and Mubadala. "I am thrilled that such a prestigious group have come forward to invest in UpStream in such a significant way," Nick Loporcaro, UpStream Board Chair.