Adaptimmune Therapeutics to merge with TCR² Therapeutics.

Adaptimmune Therapeutics, a developer of T-cell therapies for solid tumors, agreed to merge with TCR² Therapeutics, a clinical-stage cell therapy company. Adaptimmune shareholders will own approximately 75% of the combined company and TCR2 stockholders will own approximately 25% of the combined company. “This strategic combination takes two technologically and culturally aligned companies at the forefront of their fields and combines them to create a preeminent cell therapy company for solid tumors. The combined company will drive forward its pipeline of cell therapies aimed at treating multiple cancers with high unmet medical needs. This includes gaining approval for the first engineered TCR T-cell therapy for a solid tumor – afami-cel for the treatment of synovial sarcoma. With our cash runway anticipated to be extended into 2026 and covering multiple clinical catalysts in cancers with significant market potential, the combined company is well placed to develop cell therapies as a mainstream option for people with cancer," Adrian Rawcliffe, Adaptimmune CEO.